Known limitations in Clinical Trial data

If you notice missing information or inaccuracies when working with our clinical trial data, this may be the result of the following factors:

Rare Disease Coverage

Currently, our database focuses primarily on diseases that have received FDA orphan designations. This means our coverage includes these specific conditions and their associated Health Product Comparisons (HPCs), but may not encompass all rare diseases.

Drug Target Relationships and Diseases/Conditions

We’re enhancing the mapping of drug-target relationships to specific diseases and conditions in clinical trial data, ensuring more accurate links between biological entities like genes or proteins and their real-world impact. As part of this effort, we’re refining quantitative mapping scores for greater precision, though challenges remain due to inconsistencies in trial condition data.

Trial Identifiers

Some of the older trials in our database use obsolete identifiers, which can complicate searches and data retrieval.

Study Start and End Dates

Some trials have incorrect start and end dates reported on clinicaltrials.gov. For example https://go.drugbank.com/clinical_trials/NCT03591926 lists the start date as 1900. To work around this issue, you can check the record history on clinicaltrials.gov. In previous records, the date is often recorded correctly. This issue is most common with clinical trials where the status is “withdrawn”.

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